Objective:The Ki-67 protein is frequently employed in pathological immunohistochemistry to indicate cell proliferation activity.The principal aim of this study was to examine the impact of stratified management of Ki-67 on the clinicopathological characteristics and prognosis of patients with small-cell lung cancer(SCLC).Methods:A total of 175 patients with SCLC who underwent surgical treatment were included in the study,with available data on the results of postoperative immunohistochemistry of the Ki-67 protein.A retrospective analysis was conducted to investigate the correlwildlife medicineation between the protein and various clinicopathological features of SCLC,as well as its impact on survival.Results:The cut-off value for the Ki-67level was determined to be 75% through receiver operating characte确认细节ristic(ROC) analysis.selleck BelumosudilAn elevated Ki-67 level was found to be associated with preoperative chemotherapy,preoperative radiotherapy,T stage,TNM staging,and lymph node involvement.The results of the survival analysis indicated that…